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Item: 276371812154
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All returns accepted:Returns Accepted
Item must be returned within:30 Days
Refund will be given as:Money back or replacement (buyer’s choice)
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Expiration Date:08/25
Country/Region of Manufacture:United States
Formulation:Capsule
Type of Diet:Natural
Number of Pills:150
Ingredients:Mushroom,Turkey Tail
JHS Natural Products:JHS Natural Products
Active Ingredients:Mushroom,Coriolus
Features:Organic,Natural
Main Purpose:Dietary Supplement
Administration:Oral
Type:Extract
Coriolus Super Strength (Coriolus versicolor) a.k.a. Trametes versicolor, Turkey Tail or PSK Hot water extracts of Coriolus Versicolor are one of the most effective and best selling immune support supplements in the world, and the most widely used immune support supplement in Japan.* The only US government funded study ever done on a medicinal mushroom supplement ? funded by the NIH ? is currently being conducted on a hot water extract of Coriolus versicolor at Bastyr University in Seattle and the University of Washington (a.k.a. Trametes Versicolor, or Turkey Tail.) The immune health benefits of hot water extracts of Coriolus have been verified in hundreds of studies and multiple human clinical trials, making Coriolus Versicolor one of the most thoroughly researched medicinal mushrooms ever studied or used for immune support.* Turkey Tail Mushroom Coriolus Versicolor is known as Yun zhi in China and Kawaratake in Japan. In the U.S., it is also known as the Turkey Tail mushroom and by its scientific name, Trametes Versicolor. Coriolus Versicolor is likely the most common shelf fungus in the world. The NIH is currently funding a seven year study on Coriolus versicolor at Bastyr University in Seattle Washington. This study started out using an unextracted Turkey Tail mushroom supplement made by another U.S. based mushroom company for the first eighteen months, but dropped that unextracted supplement from the study in 2010 and replaced it with PSK, a hot water extract of Coriolus versicolor made in Japan. Only three women were tested in the first stage of this NIH study, and two of the three women tested showed no effect on immune health when taking the unextracted supplement. One of the three women tested showed a slight movement in NK cell activity when taking 6 grams of the unextracted powder twice a day (a massive dose for any kind of supplement.) However, this was nothing close to the overall benefit for immune health that the researchers were expecting ? so, as mentioned, they dropped the unextracted Turkey Tail supplement from the NIH study and replaced it with a hot water extract, the effective form of the supplement sold by Mushroom Science.* This was to be expected; the researchers used data from studies on hot water extracts to get the NIH grant money to begin with. It was surprising that the researchers chose to study unextracted mushroom powder at all. There is no data on unextracted mushroom or mycelium powder in the scientific literature and unextracted medicinal mushrooms have never been used in traditional herbal practice. JHS Coriolus Super Strength formula is carefully prepared with a multistep hot water extraction process, and delivers the same concentration of immune supporting polyscaccharides as the PSK tested in the highly regarded Japanese research (also known as Krestin, or Polysaccharide K).* Coriolus versicolor extracts have been available for decades in herb shops in the Chinatown sections of cities like San Francisco. A Mushroom Science employee first purchased one there in 1989, but they were not the same potency as the PSK used in the Japanese research. Starting in 1994, JHS Natural Products was the first company to offer a Coriolus extract that did match the potency of the PSK used in the Japanese research (a.k.a. Krestin). We use the N.M.R. image from the U.S. manufacturing patent for PSK, a molecular fingerprint, to ensure we are offering our customers the exact same extract used and sold in Japan under the brand name PSK or Krestin. JHS is still the only company offering a Coriolus versicolor supplement matching the potency of the PSK used in the Japanese and U.S. research. In other words, you will not find a more potent Coriolus (Turkey Tail) supplement available for purchase. There are some companies claiming that PSK and PSP can only be extracted from the mycelium (the vegetative stage), and not from the mushroom (the fruit body), however, this is not true. In the original U.S. Patent filed on the extraction process for making PSK (now expired), the inventors make the following statement; ?The term ?fungus belonging to the Coriolus genus? used herein is to be understood as referring to the fruit bodies and/or mycelia of the above mentioned species of fungi? (U.S. Patent 4,229,570, Oct. 21, 1980). *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Other names: Trametes versicolor, Turkey Tail Other ingredients: Vegetarian Capsule (cellulose), Coriolus versicolor mycelium, myceliated rice. Suggested use: Adults, take 1-3 capsules, twice daily, on an empty stomach. Warnings: Keep out of reach of children. Do not use if allergic to mushrooms, pregnant or breast feeding. Do not use if safety seal around top of bottle is missing or broken. Store at room temperature, with lid closed. Mushrooms or Mycelium? As mentioned in the Product Description area some companies claim that PSK and PSP can only be extracted from the mycelium, not the mushrooms, which is not true according to the U.S. Patent filed by the original inventors of PSK. It is true that the pharmaceutical company that first manufactured PSK for the Japanese market preferred to extract PSK from mycelium grown through liquid fermentation, also known as submerged culture, because this process does make more sense for their business model. The pharmaceutical company already owned the equipment needed to produce the mycelium, the stainless steel fermenters or bio-reactors, and they are able to grow a batch of mycelium in 48-72 hours, producing the raw material quickly, when needed. It can take up to 4-5 months to grow a crop of Coriolus versiciolor mushrooms on wood. However, this is the method we prefer. Wood is what the mushrooms grow on in nature, and it provides a far more complex nutrient base than mycelium grown on rice or grown in liquid. In the U.S.Patent detailing the extraction process the inventors offered ?Proofs? of the extraction process, where they extracted ?PSK? from both the mycelium and the mushroom fruit bodies. However, the PSK extracted from the mushrooms had higher levels of immune activity as compared to the PSK extracted from the mycelium.* Clinical Research The research shows that the polysaccharide portion of the extract enhances the cell-mediated immune response.* The 1-4, 1-3, 1-6 linked beta glucans that make up the backbone of the polysaccharide molecule act as a biological response modifier and have been found to support and enhance Natural Killer cell function, to stimulate depressed lymphocyte proliferation, and to support the healthy growth of white blood cells.* The research also shows these constituents to be effective at supporting normal cell growth, improving cell-mediated cytotoxicity, and increasing interleukin-2 production and T-cell proliferation.* Selected Clinical Studied The results of an eight-year human clinical study, published in 1990, recorded substantial benefit from the daily use of a Coriolus polysaccharide extract (obtained through hot-water extraction). The group receiving the Coriolus extract experienced significant improvements in immune health as compared to the group receiving the placebo, with the leukocyte activity of the Coriolus group showing ?remarkable enhancement.?* It was concluded that ?the beneficial effects were probably due to the activation of leukocyte function as one of the many biological-response-modifying activities induced by Coriolus.? In a study published in Lancet, a Coriolus polysaccharide extract containing the 1-4, 1-3, 1-6 linked beta glucans was found to have a ?restorative effect in patients who have been immuno-suppressed.?* Extraction Information Hot-water extracts from both the fruit body and the mycelium are used in current clinical practice and the published research. The active constituents, the protein-bound polysaccharides and the polysaccharide peptides, are found in the cell walls of both, although extracts from the fruit body (the mushroom), have shown higher levels of immune activity.* Coriolus Super Strength is isolated using a multi-step hot-water extraction process, creating the highest possible concentrations of the polysaccharides examined in the Japanese research on PSK. As these compounds are difficult to extract and easily degraded with excessive heat, NMR and linkage analysis are used to ensure product quality. *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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